Key beneficial properties
Saccharomyces boulardii is a probiotic yeast strain distinguished from other saccharomycetes by its resistance to antibiotics and its ability to grow at human body temperature
Resistance to antibiotics
Unlike bacterial probiotic cultures, S. boulardii is naturally unaffected by antibacterial medicines, allowing it to be used in supplements alongside antibiotic therapy.
Thermotolerance at body temperature
Capable of remaining metabolically active at 37°C — a property that distinguishes this strain from most other yeasts of the genus Saccharomyces.
Transient activity
It does not permanently colonise the intestine but passes through the digestive tract in transit, which is a characteristic difference from bacterial probiotic cultures.
Technological stability
The strain is resistant to freeze-drying and storage conditions, which is important for the industrial production of raw materials.
Importance for the Body’s Daily Functioning
Probiotic microorganisms are natural representatives of the human microbiota and traditional food fermentation cultures used in dietary supplements.
Depending on the genus, they colonise different parts of the digestive tract or are used outside the body in the production of fermented foods.
They serve as core cultures for a wide range of fermented products, including fermented dairy products, cheeses and silage, as well as probiotic dietary supplements.
For industrial use, the key parameters include strain stability during cultivation, resistance to processing conditions such as temperature, pH and freeze-drying, and compliance with CFU requirements.
Strain-specific characteristics determine whether a culture is suitable for a particular production process.
01.Fermentation Activity
Produce organic acids that affect the pH of the fermentation environment
02.Strain-Specific Stability
Resistance to cultivation and storage conditions varies between strains
03.Compatibility in Formulations
Used individually or in combination with other probiotic cultures
04.Controlled Concentration and Properties
Viability is confirmed through laboratory testing at every stage of production; specific parameters depend on the genus and strain
Why manufacturers choose Saccharomyces from BTU Pharma?
We offer biomass produced through a complete manufacturing cycle with quality control at every stage — from strain cultivation to finished raw material for industrial use
Complete manufacturing cycle
Cultivation and stabilisation of biomass at our own production facilities.
Quality control
Laboratory control of culture purity at every stage.
Scientific support
Selection of strains in cooperation with microbiologists according to the customer’s requirements.
Flexible supply formats
Live biomass, freeze-dried material and concentrate — subject to agreement.
Strains we grow
Industrial applications of Saccharomyces boulardii biomass
Food industry
Raw material for functional foods enriched with a probiotic yeast culture.
Agriculture
A component of feed yeast cultures for livestock production.
Pharmaceutical industry
A primary raw material for the production of dietary supplements and probiotic products based on yeast cultures.
Veterinary industry
A component of feed additives intended to support digestion in animals.
Cosmetology
Yeast extracts and lysates are used in skincare cosmetics.
Ecology and waste recycling
Yeast biomass is used in organic waste processing.
Planning to Purchase or Develop a Saccharomyces-Based Product?
Saccharomyces boulardii is a probiotic yeast strain used in dietary supplements due to its natural resistance to antibiotics, thermotolerance and transient activity in the digestive tract. Unlike baker’s or brewer’s yeast, this strain is specifically intended for use in pharmaceutical and dietary products.
BTU Pharma plans to carry out full-cycle cultivation of S. boulardii biomass — from strain cultivation to a ready-to-use raw material form, with laboratory quality control at every stage.
Benefits of working with BTU Pharma:
- More than 25 years of experience in cultivating microorganisms
- Flexible supply formats: concentrate, freeze-dried material, bulk and OEM
- Laboratory quality control at every stage of production
Contact our B2B department to discuss technical requirements and supply volumes.